A Framework for Developing and Evaluating Algorithms for Estimating Multipath Propagation Parameters from Channel Sounder Measurements

A framework is proposed for developing and evaluating algorithms for extracting multipath propagation components (MPCs) from measurements collected by channel sounders at millimeter-wave frequencies. Sounders equipped with an omnidirectional transmitter and a receiver with a uniform planar array (UPA) are considered. An accurate mathematical model is developed for the spatial frequency response of the sounder that incorporates the non-ideal cross-polar beampatterns for the UPA elements. Due to the limited Field-of-View (FoV) of each element, the model is extended to accommodate multi-FoV measurements in distinct azimuth directions. A beamspace representation of the spatial frequency response is leveraged to develop three progressively complex algorithms aimed at solving the singlesnapshot maximum likelihood estimation problem: greedy matching pursuit (CLEAN), space-alternative generalized expectationmaximization (SAGE), and RiMAX. The first two are based on purely specular MPCs whereas RiMAX also accommodates diffuse MPCs. Two approaches for performance evaluation are proposed, one with knowledge of ground truth parameters, and one based on reconstruction mean-squared error. The three algorithms are compared through a demanding channel model with hundreds of MPCs and through real measurements. The results demonstrate that CLEAN gives quite reasonable estimates which are improved by SAGE and RiMAX. Lessons learned and directions for future research are discussed.Comment: 17 page

Combined Aplasia of Sphenoid, Frontal, and Maxillary Sinuses Accompanied by Ethmoid Sinus Hypoplasia

Objective: To report the case of a woman who had combined aplasia of sphenoid, frontal, and maxillary sinuses accompanied by ethmoid sinus hypoplasia

Absence of the epiglottis in an infant with pierre robin sequence

Epiglottis anomaly associated with Pierre Robin sequence (PRS) is a rare occurrence. Most infants with PRS have presented life-threatening symptoms of respiratory distress and severe feeding problems that usually end with death. To the knowledge of the authors, this is the first reported case of epiglottis agenesis associated with PRS. The clinician must be aware of this unusual presentation in a PRS, and the presented case reveals the challenges in the treatment of the respiratory and feeding problems. This case is discussed with a review of the literature. © 2010 Elsevier Ireland Ltd. All rights reserved

Iris Juvenile Xanthogranuloma Presenting with Hypopyon

Purpose: To report a case an iris juvenile xanthogranuloma presenting with hypopyon. Case report: A 45-day-old infant was referred to our clinic for unilateral hypopyon. Slit-lamp examination revealed a 2 mm hypopyon in the left eye while visible areas of the iris were normal. Fundus examination was normal. Topical corticosteroids and antibiotics were initiated. The hypopyon regressed to 0.5 mm after 2 weeks of treatment. The now visible peripheral iris revealed an inferotemporal yellow-brown iris mass. Clinical findings were consistent with juvenile xanthogranuloma of the iris. The patient was referred to the pediatrics department which revealed no systemic involvement. Two months after total regression of hypopyon, the baby presented with a 3 mm spontaneous hyphema causing 50 mmHg intraocular pressure. The patient was followed with topical corticosteroids and antiglaucomatous drops until the hyphema was resolved. Conclusion: ocular involvement, which is the most common extracutaneous 15 manifestation of juvenile xanthogranuloma, should be considered in the differential diagnosis of hypopyon and/or hyphema in young children

The Effect of Polychlorinobiphenyls on Premature Puberty in Girls

WOS: 00044520410400

A Rhinolith Surrounded by a Nasal Polyp

Rhinoliths are uncommon mineralized nasal mass in children and adolescents. We reported a case of unilateral rhinolith that presented as a nasal polyp. A 29-year-old woman who had right-sided nasal purulent discharge, nasal obstruction, intermittent epistaxis, and posterior nasal drip for 6 months was admitted to our department. Nasal examination revealed a nasal mass between the inferior turbinate and the nasal septum, presenting as a nasal polyp or a nasal tumor. Paranasal sinus computed tomographic scan confirmed a calcified mass in soft tissue. We removed the rhinolith and the soft tissue that was around it with a transnasal endoscopic approach. Histologic analysis of the soft tissue identified inflammatory nasal polypoid tissue

Fibromyalgia syndrome in patients with chronic sinusitis

Aims: Fatigue, diminished vitality, and increased bodily pain are common symptoms of chronic rhinosinusitis. On the other hand, there is an increased prevalence of rhinosinusitis symptoms among patients with unexplained chronic fatigue and/or bodily pain. Fibromyalgia syndrome is characterized by widespread pain and fatigue. In this Study we aimed to determine the prevalence of fibromyalgia among patients with chronic sinusitis

Wideband Synthetic-Aperture Millimeter-Wave Spatial-Channel Reference System With Traceable Uncertainty Framework

This paper describes a wideband synthetic-aperture system and the associated Fourier processing for generating high-resolution spatial and temporal estimates of the signal propagation environment in wireless communication channels at millimeter-wave frequencies. We describe how to configure the synthetic aperture system for high angular resolution by sampling the progression of signal phase across a large planar area in space. We also show how to synthesize discrete measurements of the channel frequency response taken sequentially over a wide bandwidth to create power delay profiles (PDPs) in specified angular directions with high delay resolution. We provide a rigorous uncertainty analysis that can be made metrologically traceable to fundamental physical standards. This uncertainty framework can propagate the errors inherent in the measured signals through to the final channel estimates and derived parameters such as root-mean-square delay or angular spread. We illustrate use of the system in conjunction with two different analysis tools to extract both narrowband and wideband parameter estimates from the synthetic aperture, allowing its use as a stand-alone channel sounder or as a tool for verifying the performance of wireless devices

Molecular analysis of PROP1, POU1F1, LHX3, and HESX1 in Turkish patients with combined pituitary hormone deficiency: a multicenter study

WOS: 000355230500022PubMed ID: 25500790To investigate the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey. Seventy-six patients with CPHD were included in this study. Based on clinical, hormonal, and neuro-radiological data, relevant transcription factor genes were evaluated by Sanger sequencing and multiplex ligation-dependent probe amplification. Total frequency of mutations was 30.9 % in patients with CPHD. Frequency was significantly higher in familial patients (p = 0.001). Three different types of mutations in PROP1 gene (complete gene deletion, c.301-302delAG, a novel mutation; IVS1+2T > G) were found in 12 unrelated patients (21.8 %). Mutations in PROP1 gene were markedly higher in familial than in sporadic cases (58.8 vs. 5.3 %, p < 0.001). Homozygous complete gene deletion was the most common mutation in PROP1 gene (8/12) and was identified in six familial patients. Four different homozygous mutations [p.Q4X, novel mutations; exons 1-2 deletion, p.V153F, p.I244S] were detected in POU1F1 gene. Central precocious puberty was firstly observed in a sporadic-male patient with homozygous POU1F1 (p.I244S) mutation. A homozygous mutation in HESX1 gene (p.R160H) was detected in one patient. This study is the first to investigate specific mutations in CPHD patients in Turkey. Complete deletion in PROP1 gene was the most common mutation encountered in patients with CPHD. We believe that the results of this study will contribute to the establishment of genetic screening strategies in Turkey, as well as to the studies on phenotype-genotype correlations and early diagnosis of CPHD patients.Scientific and Technological Research Institution of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [106S277-SBAG-3488]; Scientific Research Projects Coordination Unit of Istanbul UniversityIstanbul University [2871]This work was supported by Scientific and Technological Research Institution of Turkey (Project Number: 106S277-SBAG-3488) and Scientific Research Projects Coordination Unit of Istanbul University (Project Number: 2871). The authors would like to thank Professor Olcay Neyzi, MD, of the Istanbul Faculty of Medicine, Istanbul University, for helpful discussions and critical reading of the manuscript